📌 COMPOSITION

Each capsule contains:

• Meclizine hydrochloride 25 mg
• Pyridoxine hydrochloride (Vitamin B6) 50 mg

📌 DESCRIPTION

Vomistop is an antiemetic and antinauseant combination of pyridoxine HCl and meclizine HCl. Pyridoxine HCl (vitamin B6) is a naturally occurring, water-soluble vitamin. Meclizine is a piperazine derivative; it is a sedating antihistamine with antimuscarinic properties. It is mainly used for its antiemetic action, which may last for up to 24 hours.

📌 INDICATIONS

• Pregnancy nausea and vomiting.
• Prevention and treatment of nausea and vomiting associated with a variety of conditions, including motion sickness, and for the symptomatic treatment of vertigo.

📌 DOSAGE & ADMINISTRATION

• For pregnancy nausea and vomiting: one capsule at bedtime.
• For motion sickness: 1 to 2 capsules should be taken one hour before travelling; the dose may be repeated every 24 hours if needed.
• For vertigo: 1 to 4 capsules daily in divided doses, depending on clinical response.

📌 RESTRICTIONS ON USE

Contraindications

• Hypersensitivity to the product.
• Patients taking levodopa without carbidopa should avoid products containing vitamin B6 in excess of 5 mg per day.

Precautions

Meclizine should be used with caution in patients with asthma, glaucoma or enlargement of the prostate gland.

Effect on the capacity to drive vehicles and operate machines

Patients should be cautioned against driving vehicles or using machines, as it may cause sedation.

📌 DRUG INTERACTIONS

• Meclizine, like other sedating antihistamines, may enhance the sedative effect of CNS depressants, including (alcohol, barbiturates, hypnotics, opioid analgesics, and anxiolytic sedatives).
• Pyridoxine may decrease the serum levels of levodopa, phenobarbital, and phenytoin.

📌 ADVERSE EFFECTS

Drowsiness, dry mouth, and rarely blurred vision.

📌 STORAGE INSTRUCTIONS

Store below 30°C in a dry place. Protect from light.

📌 PHARMACEUTICAL FORMS

• Vomistop Capsules: Pack of 20 capsules and hospital packs of different sizes.